Genetic approaches to neuropharmacology of ethanol, effects of alcohol on the central nervous system, the etiology and treatment of alcoholism, metabolism of alcohol and pathological effects, epidemiology of alcohol problems, environmental approaches to prevention, and translational neuroscience of alcoholism.
The Department of Health and Human Services is the Federal government's principal agency for protecting the health of all Americans and providing essential human services, especially to those who are least able to help themselves.
Uses and Use Restrictions
Alcohol research center grant funds may be used for support of core resources including, for example, salaries of center personnel, services and facilities shared by center personnel, and program enrichment activities such as symposia.
Support for individual components may include staff salaries, supplies, publication, travel and equipment.
Funds may not be used for training, although the applicant is required to demonstrate an institutional training capacity related to alcohol.
Funds may not be used for purchase of any land or the purchase, construction, preservation or repair of any building, and grantees must have sufficient laboratory facilities and reference services to carry out the grant.
Support will be provided for up to 5 years (renewable for subsequent periods) to qualifying centers selected for funding.
No annual grant may exceed $2,000,000 in total costs.
The actual amount of support awarded will depend upon the appropriateness of the proposed center budget to the approved Center program, as well as the availability of funds.
State and local governments, any domestic (nonfederal) public or private nonprofit and for-profit institution may apply for a center grant.
However, the proposed center must be affiliated with an institution, such as a university, medical center, or research center, that has the resources to sustain a long-term coordinated research program around a central theme related to problems of alcohol use and alcoholism.
An applicant institution must demonstrate the ability to attract high quality scientists, from biomedical, behavioral, and social science disciplines, who are willing to make a long-term commitment to alcohol research.
In addition, the applicant must assure that alcoholism related research and clinical training opportunities will be available.
Public and private nonprofit and for-profit organizations.
Costs will be determined in accordance with OMB Circular No. A-87 for State and local governments. For other grantees, costs will be determined in accordance with HHS Regulations 45 CFR Part 74, Subpart C, Section 74.27.
Aplication and Award Process
This program is excluded from coverage under E.O.
The standard application forms, as furnished by PHS must be used by grant applicants. This program is subject to 45 CFR Part 92 for State and local governments and Circular No. A-110 for nonprofit organizations.
Grants in support of approved applications are awarded directly to the applicant institution by the NIAAA.
Deadlines will be announced in specific Requests for Applications (RFA) to be published in the NIH Guide for Grants and Contracts. Contact Headquarters Office listed below for deadline dates.
Public Health Service Act, as amended, Sections 301 and 464J; 42 U.S.C. 241 and 42 U.S.C. 285n-2.
Range of Approval/Disapproval Time
The time from receipt of application to final action is approximately 9 to 10 months.
A principal investigator may appeal the substantive or procedural aspects of the review of his/her application to the staff of the Institute. A description of the NIH Peer Review Appeal procedures is available on the NIH home page www.nih.gov/grants/guide/1997/97.11.21/n2.html .
Support is recommended for a specified project period of up to 5 years. Prior to termination of a project period, the grantee may apply for renewal of support for a new project period. An application for renewal is processed as a competing request.
Formula and Matching Requirements
Length and Time Phasing of Assistance
The normal project period for an alcohol research center grant is 5 years. Grantees may apply for renewal of support on a competing basis. Within the project period, continuation applications must be submitted on a non-competing basis for each year of approved support. Payments will be made either on a Monthly Cash Request System or under an Electronic Transfer System. Necessary instructions for the appropriate type of payment will be issued shortly after an award is made.
Post Assistance Requirements
Centers will be required to submit detailed annual progress reports (including substantive information about research results to date, status of ongoing research, research plans for the next year and any modifications in long-term research plans).
Also, inventions reporting, financial status reports, final progress reports, and other reports are required to be filed in accordance with PHS policy.
Audits are to be carried out in accordance with the provisions set forth in 45 CFR Part 74, Subpart C, Section 74.26 and in OMB Circular No. A-133, as appropriate. In addition, grants and cooperative agreements are subject to inspection and audits by DHHS and other Federal officials. In accordance with the provisions of OMB Circular No. A-133, (Revised, June 24, 1997), "Audits of States, Local Governments, and Nonprofit Organizations," nonfederal entities that expend financial assistance of $300,000 or more in Federal Awards will have a single or a program-specific audit conducted for that year. Nonfederal entities that expend less than $300,000 a year in Federal awards are exempt from Federal audit requirements for the year, except as noted in Circular No. A-133.
Records must be retained at least 3 years; records shall be retained beyond the 3-year period if audit findings have not been received.
(Grants) FY 07 $27,276,000; FY 08 est $27,276,000; and FY 09 est not reported.
Range and Average of Financial Assistance
FY 07 $662,000 to $2,035,000; $1,685,000.
Regulations, Guidelines, and Literature
42 CFR Part 54a, Subpart E. Guidelines are included in application kits. PHS Grants Policy Statement, DHHS Publication No. (OASH) 94-50,000, (Rev.) April 1, 1994. Specific RFAs are published in the NIH Guide for Grants and Contracts.
Regional or Local Office
The Headquarters Office (National Institute on Alcohol Abuse and Alcoholism) is responsible for the administration of this program.
Program Contacts: Dr. Antonio Noronha, Director, Division of Neuroscience and Behavior: Telephone: (301) 443-7722. Dr. Ralph Hingson, Director, Division of Epidemiology and Prevention Research: (301) 443-1274. Dr. Mark Willenbring, Director, Division of Treatment and Recovery Research: (301) 443-1208. Dr. Samir Zakhari, Division of Metabolism and Health Effects: (301) 443-0799. National Institute on Alcohol Abuse and Alcoholism, NIH, Department of Health and Human Services, 5635 Fishers Lane, Bethesda, MD 20892-9304. Grants Management Contact: Judy Fox, Grants Management Officer, National Institute on Alcohol Abuse and Alcoholism, NIH, Department of Health and Human Services, 5635 Fishers Lane, Room 3023, Bethesda, MD 20892-9304. Telephone: (301) 443-4704. Use the same numbers for FTS.
Criteria for Selecting Proposals
Scientific/technical merit, the feasibility of the research, alcoholism implications and relevance to NIAAA priorities and public health issues are all considerations in determining what projects will be funded.