-The Organ Systems Branch of the Office of Centers, Training, and Resources, Office of the Director, National Cancer Institute, invites grant applications for Specialized Programs of Research Excellence (SPOREs) in organ-specific cancers.This Funding Opportunity Announcement (FOA) targets applicant

credit:

How's Your Community Doing?
Check Out it's
Community Vital Signs

institutions with demonstrated ability to conduct translational research in the prevention, etiology, screening, diagnosis, and/or treatment of human cancer.Applications may address cancer in any organ site, but each application must be organ site specific.Examples of organ sites include (but are not limited to) leukemias, lymphomas, myelomas, brain, breast, gastrointestinal (GI) system, genitourinary (GU) system, gynecologic (GYN) system, head & neck, lung, ovary, pancreas, prostate, skin, oral cavity & pharynx, bones, joints, soft tissue, eye & orbit, and endocrine system.Applicants are encouraged to consult with the NCI program staff members regarding the choice of cancer organ site.Translational research, as defined by the NCI, uses knowledge of human biology to develop and test the feasibility of cancer-relevant interventions in humans and/or determines the biological basis for observations made in individuals with cancer or in populations at risk for cancer.

-Required components of a SPORE grant application include a minimum of four translational research projects, one or more cores, and developmental research and career development programs.A required core in a SPORE is a human cancer tissue core for the particular organ site that will benefit translational research.

-SPOREs are designed to foster extended collaborations in critical areas of research among laboratory and clinical or applied scientists.Every SPORE is expected to have a robust research base in the respective cancer type, good access to patient populations, and substantial commitment from the applicant institution.Inter-SPORE collaborations and collaborations between SPOREs and other NIH programs are strongly encouraged.Each SPORE and the "network" of SPOREs are expected to conduct research that will have the most immediate impact possible on reducing incidence and mortality of human cancer.