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Targeting Persistent HIV Reservoirs (TaPHIR) (R21/R33)
The purpose of this Funding Opportunity Announcement (FOA) is to stimulate the development of innovative tools and strategies for curing HIV infection.
HIV establishes latent infection in long-lived cells that form a reservoir of virus that persists in infected individuals even after years of
treatment with highly active antiretroviral therapy (HAART).
Curing HIV infection requires innovative strategies to identify and eliminate these reservoir cells.
The task is especially difficult given the lack of HIV protein expression during latency and the low frequency of latently infected cells during treatment.
Novel approaches are therefore sought to efficiently monitor and specifically target reservoirs of latently infected cells to facilitate the testing of strategies to cure HIV infection in vivo.
HIV establishes latent infection in long-lived cells that form a reservoir of virus that persists in infected individuals even after years of
treatment with highly active antiretroviral therapy (HAART).
Curing HIV infection requires innovative strategies to identify and eliminate these reservoir cells.
The task is especially difficult given the lack of HIV protein expression during latency and the low frequency of latently infected cells during treatment.
Novel approaches are therefore sought to efficiently monitor and specifically target reservoirs of latently infected cells to facilitate the testing of strategies to cure HIV infection in vivo.
Related ProgramsDepartment of Health and Human Services
Allergy, Immunology and Transplantation Research
Department of Health and Human ServicesMicrobiology and Infectious Diseases Research
Department of Health and Human Services
Agency: Department of Health and Human Services
Office: National Institutes of Health
Estimated Funding: Not Available
Office: National Institutes of Health
Estimated Funding: Not Available
Who's Eligible
Relevant Nonprofit Program Categories
Obtain Full Opportunity Text:
http://grants.nih.gov/grants/guide/pa-files/PAR-15-041.html
Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
Non-domestic (non-U.S.) components of U. S. Organizations are eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/pa-files/PAR-15-041.html
Contact:
NIH OER WebmasterFBOWebmaster@OD.NIH.GOV
Agency Email Description:
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
Agency Email:
FBOWebmaster@OD.NIH.GOV
Date Posted:
2014-11-19
Application Due Date:
2017-04-07
Archive Date:
2017-05-08
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