This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research aimed at the characterization and discovery of neoantigens and neoepitopes in type 1 diabetes.
These include the characterization of the humoral and cell mediated autoimmune
responses elicited by these neoepitopes and neoantigens and their role in the etiology and pathophysiology of type 1 diabetes.
These studies should be integrated with the present knowledge of established epitopes and antigens (e.g.
autoantibodies for insulin, GAD65, IA-2, and ZnT8T).