The purpose of this Funding Opportunity is to establish Clinical Sites with Enhanced Diversity that collectively encompass a broad spectrum of healthcare settings and serve ancestrally and socioeconomically diverse patients with a wide range of clinical conditions, to:
1) define, generate and analyze
evidence regarding the clinical utility of genome sequencing; 2) research the critical interactions among patients, family members, health practitioners, and clinical laboratories that influence implementation of clinical genome sequencing; and 3) identify and address real-world barriers to integrating genomic, clinical, and healthcare utilization data within a healthcare system to build a shared evidence base for clinical decision-making.
Applicants to this FOA are expected to recruit a minimum of 60% of patients who come from racial or ethnic minority populations, underserved populations, or populations who experience poorer medical outcomes.
In contrast, applicants to the companion RFA HG-16-010 are expected to recruit a minimum of 25% of such patients.