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Lewy Body Dementia Center Without Walls (CWOW) (U54 Clinical Trial Not Allowed)
This FOA invites applications that will systematically and comprehensively characterize alpha-synuclein and amyloid-beta subspecies present in human Lewy Body Dementia (LBD) post-mortem brain tissue, identify toxic subspecies and potential mechanisms of toxicity, and characterize any interactions between
the proteins that may contribute to increased toxicity and/or explain selective vulnerabilities of cells/circuits.
Applications are required to include at least 3 hypothesis-driven projects that address these goals, an administrative core, and other cores as appropriate.
Applicants will be expected to focus on the use of human tissues.
All applications will be expected to include plans for developing a publicly-available library of fully characterized alpha-synuclein and amyloid-beta subspecies found in LBD.
the proteins that may contribute to increased toxicity and/or explain selective vulnerabilities of cells/circuits.
Applications are required to include at least 3 hypothesis-driven projects that address these goals, an administrative core, and other cores as appropriate.
Applicants will be expected to focus on the use of human tissues.
All applications will be expected to include plans for developing a publicly-available library of fully characterized alpha-synuclein and amyloid-beta subspecies found in LBD.
Related Programs
Department of Health and Human Services
Extramural Research Programs in the Neurosciences and Neurological Disorders
Department of Health and Human ServicesDepartment of Health and Human Services
Agency: Department of Health and Human Services
Office: National Institutes of Health
Estimated Funding: $1,400,000
Office: National Institutes of Health
Estimated Funding: $1,400,000
Who's Eligible
Relevant Nonprofit Program Categories
Obtain Full Opportunity Text:
http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-18-024.html
Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession.
Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/rfa-files/RFA-NS-18-024.html
Contact:
Agency Email Description:
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
Agency Email:
Date Posted:
2018-02-09
Application Due Date:
Archive Date:
2018-05-23
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