This Funding Opportunity Announcement (FOA) solicits collaborative research and capacity building projects that address the burden of tobacco use in low-and middle-income countries (LMIC) by (1) pursuing observational, intervention and policy research of LMIC relevance and (2) building capacity in epidemiological

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and behavioral research, prevention, treatment, communications, implementation, health services and policy research.

The level of research and research training specialization in any given project will vary based on the strengths of the particular investigators and institutions and the specific need to build capacity to support locally relevant research on tobacco control interventions.

The overall intent of the program is to encourage trans-disciplinary research to the international tobacco epidemic and to reduce the global burden of morbidity and mortality caused by tobacco use.

The program is designed to promote international cooperation between investigators in the U. S. or other high-income countries (HIC) pursuing research programs on tobacco control, and scientists and institutions in LMIC where tobacco consumption is a current or anticipated public health urgency.

The program allows U. S. and other HIC investigators to gain expertise working under LMIC-specific conditions and strengthens the research base of the U. S. and foreign institution(s), especially those institutions in LMIC.

To this end, capacity strengthening must be an integrated and significant part of the research proposal.

Note that in this FOA, the term tobacco includes both smoked and smokeless (non-combusted) forms of tobacco.