The SCIRP CTA supports research with the potential to have a major impact on the treatment or management of SCI.

Funding from this award mechanism must support a clinical trial and may not be used for preclinical research studies.

A clinical trial is defined as a prospective accrual of

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human subjects where an intervention (e.g., device, drug, biologic, surgical procedure, rehabilitative modality, behavioral intervention, or other) is tested on a human subject for a measurable outcome with respect to safety, effectiveness, and/or efficacy.

This outcome represents a direct effect on the human subject of that intervention or interaction.

Principal Investigators (PIs) seeking funding for a preclinical research project should consider one of the other award mechanisms/funding opportunities being offered.

The term “human subjects” is used in this Program Announcement to refer to individuals who will be recruited for or who will participate in the proposed clinical trial.

For more information, a Human Subject Resource Document is provided at the electronic Biomedical Research Application Portal (eBRAP) (https://ebrap.org/eBRAP/public/Program.htm).