Biosensing

The Biosensing program is part of the Engineering Biology and Health cluster, which also includes 1) the Biophotonics program; 2) the Cellular and Biochemical Engineering program; 3) the Disability and Rehabilitation Engineering program; and 4) the Engineering of Biomedical Systems program.

The

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Biosensing program supports fundamental engineering research on devices and methods for measurement and quantification of biological analytes.

Examples of biosensors include, but are not limited to, electrochemical/electrical biosensors, optical biosensors, plasmonic biosensors, and paper-based and nanopore-based biosensors.

In addition to advancing biosensor technology development, proposals that address critical needs in biomedical research, public health, food safety, agriculture, forensic, environmental protection, and homeland security are highly encouraged.

Proposals that incorporate emerging nanotechnology methods are especially encouraged.

Areas of interest include:
· multiplex biosensing platforms that exceed the performance of current state-of-the-art devices; · novel transduction principles, mechanisms and sensor designs suitable for measurement in practical matrix and sample-preparation-free approaches, including error-free detection of pathogens and toxins in food matrices, waterborne pathogens, parasites, toxins, biomarkers in body fluids, neuron chemicals, and others that improve human condition; · biosensors that enable measurement of biomolecular interactions in their native states, transmembrane transport, intracellular transport and reactions, and other biological phenomena; · biosensing performance optimization for specific health applications such as point-of-care testing and personalized health monitoring; · miniaturization of biosensors for lab-on-a-chip and cell/organ-on-a-chip applications to enable measurement of biological properties and functions of cell/tissues in vitro; · biosensing systems with integration of artificial intelligence (AI) and machine learning; · biosensors that exploit quantum correlations to develop a suite of analytical tools that will have superior performance over ordinary classical biosensing technology; and · biosensors that leverage unique electrical properties of biomolecules, such as DNA; proteins; cells; and the nervous system to develop miniaturized biomedical devices for modulating and characterization of biological species.

The Biosensors Program does not encourage proposals addressing surface functionalization and modulation of bio-recognition molecules, development of basic chemical mechanisms for biosensing applications, circuit design for signal processing and amplification, computational modeling, and microfluidics for sample separation and filtration.

Medical imaging-based measurements are outside of the scope of the program interests.

Proposals that rely heavily on descriptive approaches are given lower priority.

Proposals for optimizing and/or utilizing established methods for specific applications should be directed to programs focused on the application of sensor technology.

Innovative ideas outside of the above specific interest areas may be considered.

However, prior to submission, it is recommended that the PI contact the Program Director to avoid the proposal being returned without review.

NOTE:
Projects related to water/soil quality may be jointly supported with the Environmental Engineering program (CBET 1440).

Photonic devices with medical imaging and/or optogenetics should be submitted to Biophotonics (CBET 7236).

Devices for tissue engineering should be submitted to Engineering of Biomedical Systems (CBET 5345).

Basic chemical/biochemical sensing mechanisms should be submitted to the MPS Division of Chemistry's Chemical Measurement and Imaging program (CHE/CMI 6880).

Proposals for dynamic biosensing systems, including circuit design for signal/data processing and amplification, and sensing systems through communication and machine learning should be submitted to the ECCS Division's Communications, Circuits, and Sensing-Systems (ECCS/CCSS 7564).

INFORMATION COMMON TO MOST CBET PROGRAMS Proposals should address the novelty and/or potentially transformative nature of the proposed work compared to previous work in the field.

Also, it is important to address why the proposed work is important in terms of engineering science, as well as to also project the potential impact on society and/or industry of success in the research.

The novelty or potentially transformative nature of the research should be included, as a minimum, in the Project Summary of each proposal.

The duration of unsolicited proposal awards in CBET is generally up to three years.

Single-investigator award budgets typically include support for one graduate student (or equivalent) and up to one month of PI time per year (awards for multiple investigator projects are typically larger).

Proposal budgets that are much larger than typical should be discussed with the program director prior to submission.

Proposers can view budget amounts and other information from recent awards made by this program via the “What Has Been Funded (Recent Awards Made Through This Program, with Abstracts)” link towards the bottom of this page.

Faculty Early Career Development (CAREER) program proposals are strongly encouraged.

Award duration is five years.

The submission deadline for Engineering CAREER proposals is in July every year.

Learn more in the CAREER program description.

Proposals for Conferences, Workshops, and Supplements:
PIs are strongly encouraged to discuss their requests with the program director before submission of the proposal.

Grants for Rapid Response Research (RAPID) and EArly-concept Grants for Exploratory Research (EAGER) are also considered when appropriate.

Please note that proposals of these types must be discussed with the program director before submission.

Grant Opportunities for Academic Liaison with Industry (GOALI) proposals that integrate fundamental research with translational results and are consistent with the application areas of interest to each program are also encouraged.

Please note that RAPID, EAGER, and GOALI proposals can be submitted anytime during the year.

Details about RAPID, EAGER, and GOALI are available in the Proposal & Award Policies & Procedures Guide (PAPPG), Part 1, Chapter II, Section E:
Types of Proposals.

Compliance:
Proposals that are not compliant with the Proposal & Award Policies & Procedures Guide (PAPPG) will be returned without review.

Related Programs

Engineering Grants

National Science Foundation


Agency: National Science Foundation

Office: National Science Foundation

Estimated Funding: $7,600,000


Who's Eligible


Relevant Nonprofit Program Categories





Obtain Full Opportunity Text:
NSF Program Desccription PD-20-7909

Additional Information of Eligibility:
Notice of Intent

Full Opportunity Web Address:
http://www.nsf.gov/funding/pgm_summ.jsp?pims_id=505720

Contact:


Agency Email Description:
If you have any problems linking to this funding announcement, please contact

Agency Email:


Date Posted:
2019-09-12

Application Due Date:


Archive Date:
2019-10-21



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