The Centers for Disease Control and Prevention (CDC) National Center for Injury Prevention and Control (NCIPC) is soliciting investigator-initiated research proposals to demonstrate the effectiveness of a clinical intervention informed by an evidence-based guideline to:
a) improve mild traumatic brain

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injury (mTBI) outcomes in children and adolescents, and b) reduce disparities in TBI-related care and outcomes.

1. What type of disparities in mTBI-related processes and outcomes currently exist in a healthcare system prior to implementation of CDC’s Pediatric mTBI Guideline? 2. Does implementation of CDC’s Pediatric mTBI Guideline in a healthcare system result in a reduction of health disparities vis a vis improved process and health outcomes? Applicants are encouraged to supplement the guideline implementationApplicants are expected to focus on the following research questions:
with added outreach efforts to children experiencing disadvantage and implementation strategies to address specific TBI-related care and health disparities.

For the purposes of this NOFO, mTBI-related processes and outcomes include those related to the identification and treatment of an mTBI (e.g., discharge instructions, counseling regarding return to school and return to play, and communication with the school about symptoms, recovery, accommodations) as well as health outcomes.

An indicator of disparate care might be length of time between injury and diagnosis and treatment of an mTBI or the recovery trajectory of an mTBI.

Disparities (health outcomes seen to a greater or lesser extent between populations) may be related to various factors of the injured child or adolescent, their family or neighborhood, or community, such as race, gender, sexual identity, disability, socioeconomic conditions, or geographic location.