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Viral INfections in the Young Lung- The VINYL Clinical Consortium- Data Analytics and Coordinating Center (DACC)(U24 Clinical Trial Optional)
The objective of this program is to create a consortium of clinical sites that will perform deep phenotyping in 1500 babies, infants, and toddlers (0-2 years of age) with viral lower respiratory tract infections (LRTI) and hospitalized with acute bronchiolitis, pneumonia and/or the pediatric acute respiratory
distress syndrome (PARDS), and longitudinal follow up of participants for evidence of lung disease including asthma at age 4-5 years.
Bronchiolitis, a condition unique to the young lung, is the leading cause of hospitalization for viral LRTI in 02-year-old children, including those born preterm.
There are critical knowledge gaps in defining the condition, predicting its severity, and understanding the reasons for hospitalization, including the immature host respiratory immune response to viral infection, heterogeneity in response to different viruses, current interventions, significant practice variation in diagnosis and management and subsequent impact on lung health.
Bronchiolitis, a condition unique to the young lung, is the leading cause of hospitalization for viral LRTI in 02-year-old children, including those born preterm.
There are critical knowledge gaps in defining the condition, predicting its severity, and understanding the reasons for hospitalization, including the immature host respiratory immune response to viral infection, heterogeneity in response to different viruses, current interventions, significant practice variation in diagnosis and management and subsequent impact on lung health.
Agency: Department of Health and Human Services
Office: National Institutes of Health
Estimated Funding: $45,000,000
Office: National Institutes of Health
Estimated Funding: $45,000,000
Who's Eligible
Relevant Nonprofit Program Categories
Obtain Full Opportunity Text:
https://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-008.html
Additional Information of Eligibility:
Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; U. S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.
Non-domestic (non-U.S.) components of U. S. Organizations are eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-26-008.html
Contact:
Agency Email Description:
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Agency Email:
Date Posted:
2025-09-18
Application Due Date:
Archive Date:
2025-12-16
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