Emerging Infections Programs

The purpose of the Emerging Infections Programs (EIP) is to assist in local, state, and national efforts to prevent, control, and monitor the public health impact of infectious diseases.

The EIP cooperative agreement was formed in 1995 as a key component of CDC s national strategy to address and
reduce emerging infectious disease (EID) threats.

The EIP is a population-based network of state health agencies and their collaborators, including (but not limited to) academic institutions, local health departments, public health and clinical laboratories, infection control professionals, and healthcare providers.

The network plays a critical role in conducting surveillance and applied epidemiologic and laboratory research, implementing and evaluating prevention and intervention projects, and responding quickly to new infectious disease issues.

The unique strength of the EIP lies in the network s ability to quickly translate surveillance and research activities into informed policy and public health practice.
Related Programs93.283 Centers for Disease Control and Prevention_Investigations and Technical Assistance; 93.521 The Affordable Care Act: Building Epidemiology, Laboratory, and Health Information Systems Capacity in the Epidemiology and Laboratory Capacity for Infectious Disease (ELC) and Emerging Infections Program (EIP) Cooperative AgreementsExamples of Funded Projects

Fiscal Year 2013: No Current Data Available Fiscal Year 2014: Activities for this program fall into the following general categories: (1) active surveillance; (2) applied public health epidemiologic and laboratory activities; (3) implementation and evaluation of pilot prevention/intervention projects; and (4) flexible response to public health emergencies.

Activities: (1) address issues that the EIP network is particularly suited to investigate; (2) maintain sufficient flexibility for emergency response and new problems as they arise; (3) develop and evaluate public health interventions to inform public health policy and treatment guidelines; (4) incorporate training as a key function; and (5) prioritize projects that lead directly to the prevention of disease (http://wwwlink.cdc.gov/ncezid/dpei/eip).

Over the past 18 years, the EIPs have proved to be a national resource for conducting active, population-based surveillance and special studies for invasive bacterial diseases, foodborne pathogens, healthcare associated infections (HAIs), influenza, and many other infectious diseases.

The network has been instrumental in measuring the impact of the 7-valent pneumococcal conjugate vaccine, informing and evaluating treatment guidelines for Group B Streptococcus, estimating the burden of foodborne illness, documenting the emergence of community-associated methicillin-resistant Staphylococcus aureus, and monitoring the safety of the 2009 H1N1 vaccine as part of the influenza vaccine safety network.

Fiscal Year 2015: Project same as 2014.

Agency - Department of Health and Human Services

The Department of Health and Human Services is the Federal government's principal agency for protecting the health of all Americans and providing essential human services, especially to those who are least able to help themselves.

Website Address


Program Accomplishments

Fiscal Year 2013: n/a. Fiscal Year 2014: 10 continuation applications were received and 10 awards were granted. Fiscal Year 2015: It is anticipated that FY15 continuation funding will be provided for all 10 grantees funded in FY14.

Uses and Use Restrictions

Recipients may only expend funds for reasonable program purposes, including personnel, travel, supplies, and services, such as contractual.

Funding under this program will support activities that fall within the following general activities: (1)active surveillance; (2) applied public health epidemiologic and laboratory activities; (3) implementation and evaluation of pilot prevention/intervention projects; and (4) flexible response to public health emergencies.

Activities: (1) address issues that the EIP network is particularly suited to investigate; (2) maintain sufficient flexibility for emergency response and new problems as they arise; (3) develop and evaluate public health interventions to inform public health policy and treatment guidelines; (4) incorporate training as a key function; and (5) prioritize projects that lead directly to the prevention of disease (http://wwwlink.cdc.gov/ncezid/dpei/eip).

The full list of restrictions for this program are included in the published Funding Opportunity Announcement for this program.

General restrictions that apply are as follows:
• Awardees may not generally use HHS/CDC/ATSDR funding for the purchase of furniture or equipment.

Any such proposed spending must be identified in the budget.
• The direct and primary recipient in a cooperative agreement program must perform a substantial role in carrying out project objectives and not merely serve as a conduit for an award to another party or provider who is ineligible.
• Funds relating to the conduct of research will be restricted until the appropriate assurances and Institutional Review Board approvals are in place.

Eligibility Requirements

Applicant Eligibility

Eligibility is limited to State governments (specifically, state health departments) or their Bona Fide Agents (this includes the District of Columbia, the Commonwealth of Puerto Rico, the Virgin Islands, the Commonwealth of the Northern Marianna Islands, American Samoa, Guam, the Federated States of Micronesia, the Republic of the Marshall Islands, and the Republic of Palau).

The EIP infrastructure depends on a direct relationship with public health agencies that have sufficient legal authority and responsibility to perform public health surveillance and response activities.

The network must also consist of definitive populations large enough to adequately determine disease burden, evaluate large scale interventions, and impact public health policy decisions.

Beneficiary Eligibility

Beneficiaries of this program include State and local health departments, the District of Columbia, U.S. Territories, and the general public.


Allowable costs will be determined in accordance with OMB Circular No. A-87 for State, Local, and Indian Tribal governments. OMB Circular No. A-87 applies to this program.

Aplication and Award Process

Preapplication Coordination

Preapplication coordination is required.

Environmental impact information is not required for this program.

This program is eligible for coverage under E.O.

12372, "Intergovernmental Review of Federal Programs." An applicant should consult the office or official designated as the single point of contact in his or her State for more information on the process the State requires to be followed in applying for assistance, if the State has selected the program for review.

Application Procedures

OMB Circular No. A-102 applies to this program. This program is excluded from coverage under OMB Circular No. A-110. Applicants must download application forms from www.Grants.gov. Applications must be submitted electronically at www.Grants.gov. If access to the Internet is not available or if the applicant encounters difficulty in accessing the forms on-line, contact the HHS/CDC Procurement and Grant Office Technical Information Management Section (PGO TIMS) staff at (770) 488-2700 for further instruction. CDC Telecommunications for the hearing impaired or disabled is available at: TTY 1-888-232-6348.

Award Procedures

Applications that are complete and responsive will be evaluated for scientific and technical merit by an appropriate Special Emphasis Panel (SEP) in accordance with CDC SEP review policies and procedures. CDC will not review incomplete and non-responsive applications. Complete and responsive applications will undergo a SEP review process, receive a written critique and be scored according to the published review criteria. Successful applicants will receive a Notice of Award (NOA) from the CDC Procurement and Grants Office. The NOA shall be the only binding, authorizing document between the recipient and CDC. The NOA will be signed by an authorized Grants Management Officer. Initial award provides funds for the first budget period (usually 12 months) and the NOA will indicate support recommended for the remainder of the project period, allocation of Federal funds by budget categories, and special conditions, if any.

Once competing applicants have been selected by the SEP review process for the first year of funding in the project period, those selected will be eligible to submit annual non-competitive continuation applications for each successive budget period of the project period.


Contact the headquarters or regional office, as appropriate, for application deadlines.


Public Health Service Act Sections 301(a)[42 U.S.C. 241(a)], 317(k)(1)[42 U.S.C. 247b(k)(1)], and 317(k)(2)[42 U.S.C. 247b(k)(2)], as amended.

Range of Approval/Disapproval Time

From 90 to 120 days. Approval/disapproval information is typically provided to applicants within 90 to 120 days of the application due date.


Not Applicable.


Awards under this Program are typically issued for 1- to 5-year project periods. Renewals at the end of each project period are expected to be made available via publishing of a new/continuation FOA with a complete application and review/award process as described above. Annual renewals within an awarded multi-year project period are made via a non-competitive process and are subject to the availability of funding.

Assistance Considerations

Formula and Matching Requirements

This program has no statutory formula.
This program has no matching requirements.
This program does not have MOE requirements.

Length and Time Phasing of Assistance

Financial assistance is available for a 12-month budget period within a 1- to 5-year project period. Method of awarding/releasing assistance: lump sum.

Post Assistance Requirements


Program reports are not applicable.

No later than 10 days after the end of each calendar quarter, the recipients must submit a calendar quarter cash transaction report (SF-272 or top portion of the SF-425 Financial Report Form) to the Payment Management System (PMS).

The reporting schedule will be based on the requirements listed in the EIP funding opportunity announcement.

Funded applicants must provide CDC with an annual Interim Progress Report.

Additionally, funded applicants must provide CDC with a Federal Financial Report (SF 425) no more than 90 days after the end of each budget period, and a final Performance and Federal Financial Report no more than 90 days after the end of the project period.

All reports must be submitted to the Grants Management Specialist indicated in the NoA.

Additional details regarding the reporting requirements for this program are included in the published Funding Opportunity Announcements.

Federal Financial Reports (SF 425) are due no more than 90 days after the end of the budget period.

Federal Financial Reports and Progress Reports are required per the reporting schedule listed in the EIP funding opportunity announcement.


In accordance with the provisions of OMB Circular No. A-133 (Revised, June 27, 2003), "Audits of States, Local Governments, and Non-Profit Organizations," nonfederal entities that expend financial assistance of $500,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Nonfederal entities that expend less than $500,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in Circular No. A-133.


Financial records, supporting documents, statistical records, and all other records pertinent to the grant program must be retained for a minimum of 3 years after the end of a budget period, or until completion and resolution of any audit in process or pending resolution. In all cases, records must be retained until resolution of any audit questions. Property records must be retained in accordance with 45 CFR 92.42.

Financial Information

Account Identification



(Cooperative Agreements) FY 13 $0; FY 14 est $27,400,000; and FY 15 est $27,400,000 - The EIP is a long-existing program which has been through several project period continuations. Prior to establishment of this new CFDA, the EIP has been funded under CFDA 93.283.

Range and Average of Financial Assistance

Awards typically range between $1.8M to $3.4M annually with an average award of $2.7M.

Regulations, Guidelines, and Literature

Regulations governing this program are published in the specific Funding Opportunity Announcements and identified on the notices of award. Regulations are also published under 42 CFR 55b. Guidelines are available under 45 CFR 92, and also HHS Grants Policy Statement at http://www.ahrq.gov/fund/hhspolicy.htm.

Information Contacts

Regional or Local Office


Headquarters Office

Susan Gantt Scientific and Program Services Branch
Division of Preparedness and Emerging Infections
National Center for Emerging and Zoonotic Infectious Diseases
Centers for Disease Control and Prevention
1600 Clifton Road, N.E., MS C-18
, Atlanta, Georgia 30333 Email: SGantt@cdc.gov Phone: 404-639-7087

Criteria for Selecting Proposals

Applications are reviewed against specific Evaluation Criteria published in the Funding Opportunity Announcement for this program. Evaluation Criteria in the most recently published FOA include: (1) capacity to perform core functions of an EIP, (2) proposed operational plan for carrying out the specific objectives of the program, and (3) measures of effectiveness.

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