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Implementation Research to Improve Case Finding, Cascade Screening, and Treatment for Familial Hypercholesterolemia (FH) (R61/R33 Clinical Trial Required)
This milestone-driven Funding Opportunity Announcement (FOA) invites applications for single-site clinical trials that: (1) address barriers that impede population-level implementation of case finding and cascade screening (i.e., blood relatives of FH index cases are systematically contacted based on
their risk according to the pattern of inheritance); (2) explore implementation science methodologies to assess the uptake, cost-effectiveness, feasibility, and scalability of family-based cascade screening programs for familial hypercholesterolemia (FH); (3) develop or improve machine learning algorithms and data mining techniques to find high-risk individuals using electronic health records (EHRs); and (4) optimize treatment strategies and health outcomes.
Related Programs
Department of Health and Human Services
National Center on Sleep Disorders Research
Department of Health and Human ServicesCardiovascular Diseases Research
Department of Health and Human ServicesDepartment of Health and Human Services
Blood Diseases and Resources Research
Department of Health and Human Services
Agency: Department of Health and Human Services
Office: National Institutes of Health
Estimated Funding: $73,000,000
Office: National Institutes of Health
Estimated Funding: $73,000,000
Who's Eligible
Relevant Nonprofit Program Categories
Obtain Full Opportunity Text:
http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-22-006.html
Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
Non-domestic (non-U.S.) components of U. S. Organizations are eligible to apply.
Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Full Opportunity Web Address:
http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-22-006.html
Contact:
Agency Email Description:
If you have any problems linking to this funding announcement, please contact the NIH OER Webmaster
Agency Email:
Date Posted:
2020-04-16
Application Due Date:
Archive Date:
2021-06-12
