Public Health Crisis Response Cooperative Agreement

CDC seeks to enhance the nation’s ability to rapidly mobilize, surge, and respond to public health emergencies (PHEs) as identified by CDC by establishing a roster of approved but unfunded (ABU) applicants that may receive rapid funding to respond to PHEs of such magnitude, complexity, or significance


that they would have an overwhelming impact upon, and exceed resources available to, the jurisdictions.

Applicants will undergo an objective merit review process, and entities that successfully meet the requirements for approval will be placed on the ABU list.

CDC will use this ABU list for emergencies that require federal support to effectively respond to, manage, and address identified public health threats.

CDC will make funding related to this NOFO available once it has determined a public health emergency exists or is considered imminent and will be contingent upon the availability and stipulations of appropriations.

CDC will provide additional guidance and information to those on the ABU list when this NOFO is funded.

Since this NOFO is designed to collect applications prior to a PHE, applicants are encouraged to submit work plans and budgets that demonstrate their ability to respond to a PHE.

COVID-19 public health response plans, such as plans funded under CDC-RFA-TP18-1802 in 2020 are acceptable for this purpose.

If this NOFO is funded for a specific PHE, CDC will develop supplemental guidance that outlines additional work plan and budget requirements tailored to the emergency.

This NOFO is not a capacity-building funding mechanism, and it is not intended to create or establish new public health (PH) emergency management programs.

It may be used to re- establish capacity lost or diminished because of the public health crisis.

It is designed to support the surge needs of existing programs responding to a significant PHE.

CDC will provide supplemental guidance to entities on the ABU list when this NOFO is activated regarding specific activities intended to address the emergency.

CDC has strong relationships with governmental PH departments, community-based organizations, and other domestic partners and supports them for planning, capacity-building, preparedness, and response to PHEs.

This NOFO complements these ongoing capacity-building preparedness and response programs by providing a mechanism for CDC to rapidly mobilize and fund PH organizations for specific response needs.

Applicants must describe how this funding will not duplicate or supplant other federal funding.

Upon occurrence of a PHE, CDC can rapidly fund specific applicants to accelerate public health crisis response activities such as coordinating emergency operations, hiring surge staff, and conducting needs assessments to determine the resources necessary to address the public health crisis.

The NOFO also provides funding for specialized public health emergency response activities tailored to the specific public health crisis.
Agency: Department of Health and Human Services

Office: Centers for Disease Control - OPHPR

Estimated Funding: $500,000,000

Who's Eligible

Obtain Full Opportunity Text:

Additional Information of Eligibility:
This NOFO is intended for states, political subdivisions of states, and other public entities as specified in section 317(a) of the Public Health Service Act (42 USC § 247(b)).

It targets public health organizations that serve state, tribal, local, and territorial populations and are constitutionally empowered to protect the health and welfare of their respective communities, focused on executing emergency preparedness and response services.    To demonstrate existing capacity for public health emergency management, applicants must submit their response organizational charts and work plans.

If these documents are not submitted, the application will be considered non-responsive and will receive no further review.

     Local government organizations or their bona fide agents must: Serve a county population of 2 million or more or serve a city population of 400,000 or more.

Populations for county and city jurisdictions are based on the following 2019 U. S. Census resources: City and Town Population Totals: 2010-2019 ( U. S. Census – Annual Estimates of the Resident Population for Incorporated Places of 50,000 or More, Ranked by July 1, 2019, Population: April 1, 2010, to July 1, 2019 County Population Totals: 2010-2019 ( U. S. Census – Annual Estimates for 2019 Sources may be updated as census data change over time Tribal governments or their bona fide agents must be federally recognized and: Serve a population of 50,000 or more.

Applicants that meet population requirements are listed in Attachment A.

  This announcement will be open and continuous and remain on for new local and tribal applicants to accommodate population changes over the application period.


Full Opportunity Web Address:


Agency Email Description:

Agency Email:

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Application Due Date:

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