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Hermes
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative proposals to develop systemic drug delivery platforms for medical countermeasures (MCMs).
The Hermes program is explicitly seeking transformative approaches enabling the development of delivery platforms with systemic biodistribution, exceptional endosomal escape efficiency, and minimal toxicity.
Successful proposals will include a detailed description of the proposed delivery platform including 1) screening pipeline, 2) reporter systems for monitoring biodistribution and expression in animal models, 3) methods to monitor immunogenicity/toxicity, and 4) chosen therapeutic cargo and justification.
Systemic delivery platforms developed under the Hermes effort will be transferred to U. S. Government stakeholders for further development.
The Hermes program is explicitly seeking transformative approaches enabling the development of delivery platforms with systemic biodistribution, exceptional endosomal escape efficiency, and minimal toxicity.
Successful proposals will include a detailed description of the proposed delivery platform including 1) screening pipeline, 2) reporter systems for monitoring biodistribution and expression in animal models, 3) methods to monitor immunogenicity/toxicity, and 4) chosen therapeutic cargo and justification.
Systemic delivery platforms developed under the Hermes effort will be transferred to U. S. Government stakeholders for further development.
Agency: Department of Defense
Office: DARPA - Biological Technologies Office
Estimated Funding: $1,600,000
Office: DARPA - Biological Technologies Office
Estimated Funding: $1,600,000
Obtain Full Opportunity Text:
SAM.gov Contract Opportunities
Additional Information of Eligibility:
All responsible sources capable of satisfying the Government's needs may submit a proposal that shall be considered by DARPA.
See the Eligibility Information section of the BAA for more information.
Full Opportunity Web Address:
https://sam.gov/opp/3bd3f9e8f44443d7866e404406b59ce8/view
Contact:
Agency Email Description:
CDMRP Help Desk
Agency Email:
Date Posted:
2024-04-19
Application Due Date:
Archive Date:
2024-07-04
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