This FOA will provide support for assays (and associated data analysis) of repository-held samples for studies focused on an NIDDK relevant disease.
The review of applications to this FOA will consider both access to repository-held samples and funding for assays using the samples.
studies are expected to generate scientific discoveries on disease mechanisms, disease pathogenic processes, disease progression, or clinical responses.
Projects that make good use of the associated data from the clinical trials and studies, the original intent of the clinical study and/or trial are highly encouraged.
Exploratory studies and discovery research are encouraged especially when samples are not severely limited, the work is justified, and the goal is consistent with the original intent of the clinical research.