The purpose of this NOFO is to support rapid, applied research with rigorous study design (i.e., natural experiments, quasi-experimental design studies, simulation modeling, and economic evaluations) to evaluate the impact of ongoing programs, policies, and environmental improvement strategies on SDOH
and how these changes in SDOH improve chronic disease outcomes and related health disparities.
The funded sites are expected to work together to create a network.
This NOFO has three (3) components to achieve the purpose of the program:
Component A (Research Studies to Assess Inequities in Addressing Chronic Diseases):
The purpose is to support epidemiological research using studies with natural or quasi-experimental designs aimed at identifying and evaluating how inequities in chronic disease outcomes are mitigated by ongoing programs, policies, and environmental improvement strategies targeting SDOH.
Component B (Studies to Assess Health and Economic Outcomes and Disparities of Chronic Diseases):
The purpose is to support research that will apply a systems science approach to build simulation models of the interplay of SDOH factors and their relationship to chronic disease and health disparities, providing long-term estimates (e.g., 10-, 20-, 30-year) of chronic disease outcomes and disparities in quality-adjusted life-years, and the cost and cost-effectiveness of a policy, program, or strategy.
Component C (Coordinating Center):
The purpose is to support a coordinating center that provides organizational, logistic, and communication support to enhance the efficiency, productivity, and public health impact of the research centers that are funded under Components A and B.
Applicants may apply for Component A or Component B.
Applicants for Component C must apply for and be funded for Component A or Component B to be funded for Component C.