Organotypic Culture Models developed from Experimental Animals for Chemical Toxicity Screening (R43/R44 Clinical Trial Not Allowed)

This Funding Opportunity Announcement (FOA) supports Phase I (R43), Phase II (R44), Direct Phase II (R44) and Fast Track (R44) Small Business Innovative Research (SBIR) grant proposals from small businesses concerns (SBCs) to develop novel, physiologically-relevant in vitro screening systems (e.g., engineered

3-dimensional or organotypic models) using cells derived from animal species typically utilized for toxicological testing, which will replicate biological interactions and toxicological responses observed in animal tissues or organs, will produce assay data suitable for comparisons between in vitro and in vivo animal toxicology studies, and may ultimately provide alternative methods to reduce the use of animals in toxicity testing.
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Environmental Health

Department of Health and Human Services

Agency: Department of Health and Human Services

Office: National Institutes of Health

Estimated Funding: $4,000,000

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Other Eligible Applicants include the following: Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.

Non-domestic (non-U.S.) components of U. S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

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Tech Startup Prevents Human Trafficking

Chief executive Tim Ballard founded the Operation Underground Railroad, which seeks to save hundreds of children from human traffickers. Under his wing, Ballard has a software a child protection system (CPS) that he and his team had trained the Imperial County Sheriff’s office on how to use it

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