ARRA Accelerating Adoption of Comparative Effectiveness Research (CER)

Comparative effectiveness research is the conduct and synthesis of research comparing the benefits and harms of different interventions and strategies to prevent, diagnose, treat and monitor health conditions in "real world" settings.

The purpose of this research is to improve health outcomes
by developing and disseminating evidence-based information to patients, clinicians, and other decision-makers, responding to their expressed needs, about which interventions are most effective for which patients under specific circumstances."
The purpose of this program is to develop and test strategies to improve the dissemination of CER information and the resultant translation of this evidence into practice in the non-profit and private sector.

Doing so effectively would demonstrate a return on the CER investment, and, more importantly, improve the health of the patients served by a given organization.

Funds will be used to support organizations that 1) develop evidence-informed, yet innovative dissemination and translation strategies; 2) develop proposals that study the implementation of dissemination and translation strategies within their organization.

Agency - Department of Health and Human Services

The Department of Health and Human Services is the Federal government's principal agency for protecting the health of all Americans and providing essential human services, especially to those who are least able to help themselves.



Program Accomplishments

Fiscal Year 2009: No Current Data Available Fiscal Year 2010: It is anticipated that 30 applications will be received and 5-10 awards will be granted in fiscal year 2010. Fiscal Year 2011: No Current Data Available

Uses and Use Restrictions

This program is subject to the provisions of 45 CFR 74, and 45 CFR 92 as well as OMB Circular No.

A-102 (Administrative Guidelines for States and Local Governments), and OMB Circular A-110 (Administrative Guidelines for Institutions of Higher Education, Hospitals, and Other Nonprofit Organizations).

Funds may not be used for construction or renovation of buildings.

Eligibility Requirements

Applicant Eligibility

Types if institutions or organizations that can apply include integrated health care systems, integrated provider systems, academic medical centers, provider consortia, community health center networks, private payers, other non-governmental organizations that administer or directly provide health care services, and organizations that serve health care consumers.

Additional eligible applicants include University-based schools (e.g.

School of Public Policy or Public Health) and private research institutes.
Projects must meet the definition of CER in the Federal Coordinating Council Report: http://www.hhs.gov/recovery/programs/cer/cerannualrpt.pdf.

Beneficiary Eligibility

Expected beneficiaries include patients, health care providers, policymakers, and healthcare systems.

Credentials/Documentation

Nonprofit organizations must provide evidence of tax-exempt status. When projects involve the collaborative efforts of more than one organization or require the use of services or facilities not under the direct control of the applicant, written assurances of specific support or agreements must be submitted by the affected parties. OMB Circular No. A-87 applies to this program.

Aplication and Award Process

Preapplication Coordination

Preapplication coordination is not applicable.

Environmental impact information is not required for this program.

This program is excluded from coverage under E.O.

12372.

Application Procedures

OMB Circular No. A-102 applies to this program. OMB Circular No. A-110 applies to this program. Applications are submitted in response to specific funding opportunity announcements via Grants.gov. Each announcement provides specific additional instructions regarding the contents of the narrative description of the project, budget justification, forms and other required information.

Award Procedures

After the peer review of the application is completed, the Principal Investigator will be able to access his or her Summary Statement (written critique) via the eRA Commons. A formal notification in the form of a Notice of Award (NOA) will be provided to the applicant organization. Once all administrative and programmatic issues have been resolved, the Notice of Award will be generated from the awarding component to the grantee business official. The NOA signed by the grants management officer is the authorizing document.

Deadlines

Contact the headquarters or regional office, as appropriate, for application deadlines.

Authorization

American Recovery and Reinvestment Act (ARRA), Public Law 111-5; Public Health Services Act, Title 42, Section 301.

Range of Approval/Disapproval Time

From 90 to 120 days.

Appeals

Not Applicable.

Renewals

Extensions to the project period may be made if deemed appropriate by the Assistant Secretary for Planning and Evaluation.

Assistance Considerations

Formula and Matching Requirements

This program has no statutory formula.
This program has no matching requirements. This program is funded by ARRA and has no matching requirements.
This program does not have MOE requirements.

Length and Time Phasing of Assistance

Grants and cooperative agreements are generally funded on a 12-month basis. Support beyond the first year is contingent upon acceptable evidence of satisfactory progress, continuing program relevance, and the availability of funds. Method of awarding/releasing assistance: quarterly.

Post Assistance Requirements

Reports

No program reports are required.

No cash reports are required.

When multiple years are involved, grantees will be required to submit the Non-Competing Grant Progress Report (PHS 2590) annually.

The annual progress reports must include Sections a through f as described in the general PHS form 2590 instructions, as well as sections g through j as described in Section IV of the 2590 instructions.

For details regarding progress report submission, refer to http://www.ahrq.gov/fund/noncomp.htm.

If instructions on the ASPE website are different from the PHS form 2590 instructions, follow the instructions on the ASPE website.

The Progress Report is to include descriptive and evaluative comments on both completed activities and plans for the remainder of that year, including any changes foreseen in the future.

At a minimum, the reports will include descriptive comments on: progress to date measured against project aims; methodological changes implemented; key preliminary findings; significant problems and resolutions; inclusion of priority populations; and project related publications, presentations, and dissemination activities.

ASPE will provide the timetable for these progress reports.

A final Progress Report and Financial Status Report are required when an award ends.

For further details regarding grant closeout requirements, refer to http://www.ahrq.gov/fund/closeout.htm.

Financial Status Reports (FSRs; SF 269) are required annually by ASPE for ALL grant programs as described in the HHS Grants Policy Statement (see http://www.ahrq.gov/fund/hhspolicy.htm).

This report must be submitted for each budget period no later than 90 days after the close of the budget period.

A hard copy of the report should be submitted to the assigned grants management specialist.

A final Progress Report and Financial Status Report are required when an award ends.

For further details regarding grant closeout requirements, refer to http://www.ahrq.gov/fund/closeout.htm.

In addition to the standard ASPE terms of award, all funding provided under the Recovery Act will be subject to the HHS Standard Terms and Conditions for American Recovery and Reinvestment Act of 2009 (ARRA).

The full text of these terms approved for ASPE awards can be found in the following document: Standard Terms and Conditions for ARRA Awards.

Recovery Act-related reporting requirements will be incorporated as a special term of award.

A final Progress Report and Financial Status Report are required when an award ends.

For further details regarding grant closeout requirements, refer to http://www.ahrq.gov/fund/closeout.htm.

Audits

In accordance with the provisions of OMB Circular No. A-133 (Revised, June 27, 2003), "Audits of States, Local Governments, and Non-Profit Organizations," nonfederal entities that expend financial assistance of $500,000 or more in Federal awards will have a single or a program-specific audit conducted for that year. Nonfederal entities that expend less than $500,000 a year in Federal awards are exempt from Federal audit requirements for that year, except as noted in Circular No. A-133. All fiscal transactions identifiable as Federal financial assistance are subject to audit by the HHS audit agency and the Office of the Assistant Secretary for Planning and Evaluation and NIH conducts audits.

Records

In accordance with 45 CFR Part 74.53 and 45 CFR Part 92, grantees are to maintain accounting records for a minimum of 3 years after the end of a budget period. If any litigation, claim, negotiation, audit or other action involving the records has been started before the expiration of the 3-year period, the records shall be retained until completion of the action and resolution of all issues which arise from it, or until the end of the regular 3-year period, whichever is later.

Financial Information

Account Identification

75-0910-1-7-010.

Obigations

(Project Grants) FY 08 $0; FY 09 est $0; FY 10 est $14,000,000

Range and Average of Financial Assistance

ASPE has designated $300,000 to $3,000,000 in FY 2010 to fund 5-10 grants, contingent upon the submission of a sufficient number of scientifically meritorious applications.

Budget proposals are limited to $1,000,000 in total costs per year for a total of $3,000,000 in costs over 3 years. Facilities and administrative (F&A) costs requested by applicants are included in the total cost limitation. Applications with project periods that exceed 3 years or budgets that exceed $1,000,000 total costs per year will not be reviewed.

Regulations, Guidelines, and Literature

Grant administration policies (45 CFR 74 and 92) and application kits may be obtained from the ASPE Grants Management Specialist, LTS, National Institute of Allergy and Infectious Diseases, NIH, DEA, DHHS, 6700B Rockledge Drive, Room 3220, Bethesda, MD 20892-7614. Additional information about the mission and activities of the Office of the Assistant Secretary for Planning and Evaluation is available on its website at http://aspe.hhs.gov.

Information Contacts

Regional or Local Office

None.

Headquarters Office

Patrick H. Conway 200 Independence Avenue SW, Room 415-F, Washington, District of Columbia 20201 Email: patrick.conway@hhs.gov Phone: 2026907388

Criteria for Selecting Proposals

The rating criteria will be included in the FOA that requests grant proposals. The criteria typically include such concerns as the significance and usefulness of the project; the appropriateness of the intervention/measurement methodology and design; the qualifications of personnel and the sponsoring organization; and the likelihood that the work plan and budget will produce the intended results.



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