(1) Research center support coordinated studies of periodontal diseases, clinical cores, dental caries, oral biology, craniofacial disorders, oral cancer, minority oral health, and materials sciences; (2) genomic sequencing of bacterial oral pathogens; (3) metalloproteinases in developing enamel; (4) genetic basis of ectodermal dysplasia; (5) biofilms, including studies of microbial ecology, physiology and transmission; (6) prevention and control of infectious diseases including behavioral approaches, antibiotics and vaccines; (7) development of anti-streptococcal antibodies in genetically engineered plants; (8) endodontic treatment and management of oral AIDS-Kaposi's sarcoma for HIV positive patients; (9); development of HIV diagnostic assays utilizing saliva; (10) epidemiology of HIV associated opportunistic oral infections; (11) papilloma viruses in oral cancer; (12) regulated expression of extra-cellular matrix proteins in oral cancer; (13) biobehavioral aspects of temporomandibular disorders (TMD); 14)pharmacological management of TMDs; (15) brainstem mechanisms controlling jaw movement; (16) neural control of swallowing and mastication; (17) construction of chimeric salivary molecules; (18) etiology and pathology of Sjogren's syndrome; (19) guided bone regeneration with morphogenic protein; and (20) computer assisted detection of dental caries.
The Department of Health and Human Services is the Federal government's principal agency for protecting the health of all Americans and providing essential human services, especially to those who are least able to help themselves.
Funding for fiscal year 2007 is estimated as follows: 451 noncompeting research project grants at $171,443,000, 169 competing grants at $54,177,000, 34 SBIR/STTR awards at $8,330,000, 8 research centers at $15,259,000, 90 grants in the career development award program at $12,350,000, 27 other research grants at $12,275,000, and 337 positions in the NRSA program at $14,910,000.
Uses and Use Restrictions
Research Grants: Research Grants provide funds for salaries, equipment, supplies, travel, and other expenses associated with scientific investigation in the oral health sciences.
They are awarded to universities, colleges, medical and dental schools, hospitals, and other nonprofit and for-profit institutions.
Awards include investigator-initiated project grants, program project grants, center grants, career development awards to enable investigators with outstanding research potential to develop their careers, and small grants.
Individual and institutional Dentist Scientist Awards are made to provide research career development in both clinical and basic science areas.
National Research Service Awards (NRSAs) can be made directly to individuals for research training in specified biomedical areas, and can be made to institutions to enable them to accept individuals for research training.
Individuals who receive NRSAs may be obligated upon termination of the award to comply with service and payback provisions.
SBIR Phase I grants (of approximately 6-months' duration) are to establish the technical merit and feasibility of a proposed research effort that may lead to a commercial product or process.
Phase II grants are for the continuation of the research initiated in Phase I and that are likely to result in commercial products or process.
Only Phase I awardees are eligible to receive Phase II support.
STTR Phase I grants (normally 1-year duration) are able to determine the scientific, technical, and commercial merit and feasibility of the proposed cooperation effort that has potential for commercial application.
Phase II funding is based on results of research initiated in Phase I and scientific and technical merit and commercial potential of Phase II application.