Discovery and Applied Research for Technological Innovations to Improve Human Health

To support hypothesis, design, technology, or devise-driven research relation to the discovery, design, development, validation, and application of technologies related to biomedical imaging and bioengineering.

The program includes biomaterials (biomimetics, bioprocessing, organogenesis, rehabilitation,

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tissue engineering, implant science, material science, interface science, physics and stress engineering, technology assessment of materials/devices), biosensors/biotransducers (technology development, technology assessment, development of algorithms, telemetry), nanotechnology (nanoscience, biomimetics, drug delivery systems, drug bioavailability, microarray/combinatorial technology, genetic engineering, computer science, technology assessment), bioinformatics (computer science, information science, mathematics, biomechanics, computational modeling and simulation, remote diagnosis and therapy), imaging device development, biomedical imaging technology development, image exploitation, contrast agents, informatics and computer sciences related to imaging, molecular and cellular imaging, bioelectrics/biomagnetics, organ and whole body imaging, screening for diseases and disorders, and imaging technology assessment and surgery (technique development and technology development).
Related Programs

Examples of Funded Projects

(1) Studies to fully utilize multiple forms of information (MRI and EEG); (2) Construction and investigation of a scanning equalization digital radiography (SEDR) system to over come the problems with projection x-ray imaging; (3) Utilization of functional magnetic resonance imaging (IMRI) technique based on the blood oxygen level dependent (BOLD) contrast to provide a robust and noninvasive tool for studying functional processing of neural network at physiological and pathological conditions; (4) Development of two complimentary intervention devices for treating stroke victims: mechanical clot extraction system and a neurovascular stent; (5) Development of molecular array biosensors using metallic nanoparticle clusters to capture in parallel a large number of molecular species from very small samples typical of most collection procedures; and (6) Production of nanoparticles containing agents that will have cell and tissue specificity, and demonstration of the effectiveness of these nanoparticles in attaining the intended specificity in tissue permeation and localization.

Agency - Department of Health and Human Services

The Department of Health and Human Services is the Federal government's principal agency for protecting the health of all Americans and providing essential human services, especially to those who are least able to help themselves.