The FY24 PRMRP Impact Award supports applied research, defined as use-inspired and practice-oriented science that brings together outcomes from basic research, and insights from the real-world environment, to foster clinical applicability.

The intent of the Impact Award is to translate the fundamental

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understanding of underlying mechanisms toward practical applications that have the potential for major near-term impact on patients affected by one of the diseases and conditions included in the FY24 PRMRP Topic Areas.Proposed research should refine mature concepts and ideas into translatable solutions with a view toward evaluating technical feasibility of promising new pharmacological agents, knowledge products, behavioral and rehabilitation interventions, diagnostic and therapeutic techniques, clinical guidance, and/or emerging approaches and technologies.

The FY24 PRMRP Impact Award is not intended to support basic research.For the purposes of this funding opportunity, basic research is defined as exploratory science directed toward greater knowledge or understanding of the fundamental aspects of phenomena or outcomes, without specific applications toward process and products.

Examples include, but are not limited to, high-risk/high-gain approaches, mechanistic studies, and preliminary data generation/validation.

Applicants seeking funding for research that meets this definition should consider one of the other FY24 PRMRP program announcements being offered.

For information about these award mechanisms, see Section II.A.1, FY24 PRMRP Research Development Pipeline.