Bench Testing Therapeutic/Indication Pairing Strategies (UG3/UH3)

This Funding Opportunity Announcement (FOA) invites applications for support of pre-clinical studies to repurpose existing experimental or FDA approved drugs or biologics (existing therapeutics) that have already begun or completed at least a Phase l trial.

The hypothesis for proposed studies


must be developed using innovative processes to identify the therapeutic/indication pair.

Examples include independent crowdsourcing strategies (e.g.,,, or any website that lists experimental therapies), or use of computational algorithms.

The initial UG3 award will support the development of milestone-driven rigorous, pre-clinical target engagement and/or efficacy studies.

Once UG3 pre-clinical milestones have been met, the UH3 award may be made to support clinical trial planning:
this includes complete planning, design, and preparation of the documentation necessary for implementation of Phase I and/or Phase II clinical trials for a new therapeutic use.
Related Programs

National Center for Advancing Translational Sciences

Department of Health and Human Services

Agency: National Institutes of Health


Estimated Funding: $1,542,548

Who's Eligible

Obtain Full Opportunity Text:

Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.

Non-domestic (non-U.S.) components of U. S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Full Opportunity Web Address:


Agency Email Description:

Agency Email:

Date Posted:

Application Due Date:

Archive Date:

The Festival of Inclusive Arts, organized by the Arts with the Disabled Association, gives disabled performers a chance to shine.

Not for Profit Jobs in Nebraska

  Executive Director Jobs
  Substance Abuse Jobs
  Program Director Jobs
  Executive Director Jobs
  Social Services Jobs

More Federal Domestic Assistance Programs

Advanced Surveillance Program (ASP) | The U.S. President"s Emergency Plan for AIDS Relief Programs | South Carolina SNAP Recipient Trafficking Prosecution Pilot | ARRA-Survey and Certification Ambulatory Surgical Center Healthcare-Associated Infection (ASC-HAI) P | National Park Service Conservation, Protection, Outreach, and Education |  Site Style by YAML | | Grants | Grants News | Sitemap | Privacy Policy

Edited by: Michael Saunders

© 2004-2022 Copyright Michael Saunders