The intent of the FY19 CPMRP IIRA is to support studies that have the potential to make significant advances in research, patient care, and/or quality of life in the FY19 CPMRP IIRA Focus Area, Chronification of Pain.

Through understanding the determinates of transition from acute to chronic

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pain and development of therapies that block the process of chronification, the CPMRP seeks to prevent the manifestation of chronic pain and thus reduce the population requiring pain management interventions.

IIRA applications may involve any phase of basic, translational, and clinically oriented research, including studies in animal models, research with human anatomical substances, and research with human subjects, as well as ancillary studies associated with an existing clinical trial; however, this award may not be used to conduct clinical trials.

Multidisciplinary collaborations and innovative approaches are encouraged.