U.S. and Low- and Middle-Income Country (LMIC) HIV-Associated Malignancy Research Centers (U54 Clinical Trial Optional)

The purpose of this Funding Opportunity Announcement (FOA) is to support research on human immunodeficiency virus (HIV)-associated cancers in low- and middle-income countries (LMICs) through the formation of collaborative partnerships between investigators in United States (U.S.) and investigators in



The FOA solicits applications for Specialized Center Cooperative Agreements (U54) for research on HIV-associated cancers from research institutions in the U. S. and LMICs.

These partnerships are referred to as HIV-Associated Malignancy Research Centers (HAMRCs).

Each proposed U54 HAMRC should be based upon partnerships involving at least one U. S. institution and institutions from at least two or more LMICs.

Each HAMRC application is required to propose between two to three research projects that address questions in one scientific theme (e.g.

viral-associated cancers) that is relevant to HIV-associated malignancies in LMICs or the U. S. The proposed projects may range, as appropriate, from basic research to translational efforts as well as to population and implementation studies.

Mechanistic clinical studies that meet NIH's definition of a clinical trial will be allowed.

In addition, the proposed U54 HAMRC must include an Administrative Core and a Developmental Core.
Related Programs

Cancer Cause and Prevention Research

Department of Health and Human Services

Cancer Detection and Diagnosis Research

Department of Health and Human Services

Cancer Treatment Research

Department of Health and Human Services

Cancer Biology Research

Department of Health and Human Services

International Research and Research Training

Department of Health and Human Services

Agency: Department of Health and Human Services

Office: National Institutes of Health

Estimated Funding: $3,300,000

Who's Eligible

Obtain Full Opportunity Text:

Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession.

Full Opportunity Web Address:


Agency Email Description:
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

Agency Email:

Date Posted:

Application Due Date:

Archive Date:

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