Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) Multisite Resource and Coordinating Center (U24 Clinical Trial Required)

This FOA runs in parallel with the companion FOA (RFA-HL-22-007).

This FOA uses the bi-phasic, milestone-driven UG3/UH3 cooperative agreement mechanism (UG3/UH3), and runs in parallel with a companion FOA (RFA-HL-22-008), which seeks applications for a Data Coordinating Center (DCC).



made under this FOA will support a milestone-driven planning phase, including feasibility studies and pilot trials for up to 2 years, with possible transition to an implementation phase (UH3) for up to five additional years.

Only UG3 trials that meet the scientific milestones and award requirements of the UG3 phase may transition to the UH3 phase.

Applications submitted in response to this FOA must address both the UG3 and UH3 phases.

Applications must include plans for project management, subject recruitment and retention, scientific conduct of the trial including its design, randomization and power analysis; intervention, measurement, and statistical analysis of study results.

Performance-based milestones must be included in each phase.

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Additional Information of Eligibility:
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U. S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.

Non-domestic (non-U.S.) components of U. S. Organizations are not eligible to apply.

Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

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The World Bank’s Development Marketplace, a competitive grants program, has provided $1.4 million grants to 12 social enterprises in the northeastern states of Assam, Meghalaya and Mizoram for development activities and capacity building investments.

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