Restoring Joint Health and Function to Reduce Pain Consortium (RE-JOIN) (UC2 Clinical Trial Not Allowed) - The purpose of this Funding Opportunity Announcement is to solicit cooperative agreement applications to support interdisciplinary teams that will work together to form the Restoring
Joint Health and Function to Reduce Pain Consortium (RE-JOIN).
The goal of RE-JOIN will be to define the innervation of the different tissues, which collectively form the joints, by sensory neurons that mediate the sensation of pain.
Knowledge about the types and distribution of neurites in joint tissues will facilitate the identification of key receptors and mediators that induce pain by activating specific sensory neurons.
These mediators or their receptors will provide novel targets for reducing pain.